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Research. Case Reviews.
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From peer-reviewed studies to behind-the-scenes insights from our tri-city rounds, this is where BLT shares what we’re learning—and what’s next in pediatric neurovascular care.

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Boston – London – Toronto Collaborative Clinical Neuroscience Meeting: Key Highlights from October 27, 2023

Updated: Aug 28

On Friday, October 27, 2023, leaders in pediatric neurosurgery and neuroscience gathered at Queen Square, London, for the Boston – London – Toronto Collaborative Clinical Neuroscience Meeting. Hosted by Consultant Paediatric Neurosurgeon Gregory James, the event united three of the world’s foremost children’s hospitals — Boston Children’s Hospital/Harvard University, Great Ormond Street Hospital (UK), and the SickKids Foundation, Toronto — in a landmark collaboration supported by Amethyst Radiotherapy.


The meeting offered an unprecedented exchange of research, case studies, and surgical insights, advancing the shared mission of improving outcomes in rare pediatric neurovascular and neurological conditions.


Boston – London – Toronto Collaborative Clinical Neuroscience Meeting

Opening Remarks & Moyamoya Focus


The day opened with Greg James and Dr. Edward Smith, who set the stage for a highly engaging program. Early sessions centered on Moyamoya disease:

  • Greg James explored decision-making in asymptomatic Moyamoya, addressing when intervention is warranted.

  • Vitor Yamaki presented updates from the European Stroke Organization’s Moyamoya Guidelines, offering new international perspectives.

  • Dr. Edward Smith led a “Hot Topics” session, spotlighting the latest advances and ongoing challenges in Moyamoya research.


Innovations in Imaging & Surgical Monitoring


  • David Attwell examined the role of blood flow control at the capillary level, and its contribution to conditions such as Alzheimer’s disease and stroke.

  • Steward Boyd shared initial experiences with intraoperative EEG monitoring during Moyamoya surgery in London, a step toward enhanced surgical safety and outcomes.


Expanding Beyond Moyamoya: HHT, AVMs & Case Insights


  • Anoushka Alwis presented unique insights into infantile presentations of Hereditary Hemorrhagic Telangiectasia (HHT).

  • Dulu Silva showcased advancements in revascularisation surgery for AVM steal syndrome, highlighting evolving surgical strategies.

  • Dina Hanna shared a series of compelling recent cases from Great Ormond Street Hospital, further enriching the collaborative discussion.


Networking & Collaboration


The program concluded with opportunities for informal networking at 42–43 Queen Square and the Queen’s Larder, fostering cross-institutional relationships that will fuel ongoing collaboration.



Looking Ahead


The Boston – London – Toronto Collaborative Clinical Neuroscience Meeting reinforced the power of international cooperation in addressing rare and complex neurological conditions. By combining expertise across three leading institutions, the event advanced not only current understanding but also the framework for future research, surgical innovation, and patient-centered care.


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