London - BLT Paediatric Neurovascular Collaboration Meeting – November 14, 2025
- juliemeadows
- Nov 21
- 2 min read
Date: 14 November 2025
Great Ormond Street Hospital (GOSH), London
The BLT Paediatric Neurovascular Collaboration Meeting convened international experts, clinicians, and researchers to advance interdisciplinary understanding and treatment strategies for paediatric neurovascular conditions. The event featured a full day of academic sessions highlighting innovations in biology-driven therapies, surgical approaches, disease taxonomy, and complex case management.
Key Themes & Insights
1. Advances in Targeted and Biological Therapies
The keynote session, led by Dr. Veronica Kinsler and Dr. Maanasa Polubothu, showcased emerging biological treatments for vascular malformations, emphasizing rapid progress in molecular and genetic therapy development. Discussions underscored the growing feasibility of precision interventions tailored to specific pathogenic pathways.
2. Refining Surgical Decision-Making
Multiple presentations focused on improving patient selection and surgical outcomes:
CPA revascularisation criteria and optimisation strategies from Dr. Alfred Pokmeng See.
New insights into managing complex cerebral aneurysms in children from Mr. Dulanka Silva.
Exploration of systemic blood pressure changes following revascularisation in Moyamoya disease from medical student Taqwa Ahmad.
These talks collectively highlighted the shift toward data-driven, individualized surgical planning.
3. Precision Medicine in Paediatric Moyamoya
Dr. Laura Lehman discussed how genetic insights and precision-medicine frameworks are reshaping understanding of Moyamoya disease progression and treatment selection.
4. Disease Classification & Emerging Technologies
Dr. Edward Smith introduced a refined taxonomy of paediatric cerebrovascular disease, aiming to improve communication, research consistency, and clinical diagnostics.
Dr. Scellig Stone presented experience with MRLITT for epilepsy secondary to cavernous malformations, highlighting its growing role as a minimally invasive alternative.
5. Challenging Case Discussions
Mr. Fergus Robertson provided an in-depth overview of the Gamma Knife procedure, outlining the clinical workflow, patient selection criteria, and key steps involved in its delivery. Dr. Fozia Saeed and the GOSH team contributed additional compelling cases, fostering rich multidisciplinary dialogue.
Outcomes & Next Steps
The meeting strengthened cross-institutional collaboration, highlighted priority research areas, and identified opportunities for shared clinical pathways. Participants expressed strong interest in continued joint case reviews, expanded genetic studies in Moyamoya, and collaborative development of therapeutic targets such as TMEM16A.
The day concluded with closing remarks by Mr. Greg James and an evening social gathering that supported networking and international partnership-building.
